東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁 到查詢結果 [ subject:"Neurotoxicology." ]

切換: 標籤 | MARC模式 | ISBD

Features and management of acute and...

Cascella, Marco.

FindBook

Google Book

Amazon

博客來

Features and management of acute and chronic neuro-covid

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Features and management of acute and chronic neuro-covid/ by Marco Cascella, Elvio De Blasio.
作者:	Cascella, Marco.
其他作者:	De Blasio, Elvio.
出版者:	Cham :Springer International Publishing : : 2022.,
面頁冊數:	xix, 158 p. :ill. (some col.), digital ;24 cm.
內容註:	Introduction -- Part I. Pathophysiology of COVID-19-associated neurotoxicity -- An update on preclinical findings -- Ongoing clinical investigations -- Perspectives -- Part II. Clinical manifestations of acute neurotoxicity -- Clinical features -- CNS complications -- PNS complications -- Diagnosis -- Management -- Perspectives -- Part III. Neurological and psychiatric sequelae in COVID-19 survivors -- Clinical features -- Neurological late complications -- psychological and psychiatric sequelae -- Diagnosis -- Tools -- The role of imaging -- Preventive strategies -- Social and economic impact -- Multidisciplinary management -- Perspectives.
Contained By:	Springer Nature eBook
標題:	COVID-19 (Disease) - Pathophysiology. -
電子資源:	https://doi.org/10.1007/978-3-030-86705-8
ISBN:	9783030867058

Features and management of acute and chronic neuro-covid
Cascella, Marco.

Features and management of acute and chronic neuro-covid[electronic resource] /by Marco Cascella, Elvio De Blasio. - Cham :Springer International Publishing :2022. - xix, 158 p. :ill. (some col.), digital ;24 cm.

Introduction -- Part I. Pathophysiology of COVID-19-associated neurotoxicity -- An update on preclinical findings -- Ongoing clinical investigations -- Perspectives -- Part II. Clinical manifestations of acute neurotoxicity -- Clinical features -- CNS complications -- PNS complications -- Diagnosis -- Management -- Perspectives -- Part III. Neurological and psychiatric sequelae in COVID-19 survivors -- Clinical features -- Neurological late complications -- psychological and psychiatric sequelae -- Diagnosis -- Tools -- The role of imaging -- Preventive strategies -- Social and economic impact -- Multidisciplinary management -- Perspectives.

This book underlines how COVID-19 is a multisystem inflammatory disease and how its pathophysiology can predispose to an increased risk of neurological issues. Several scientific pieces of evidence showes the mechanisms underlying the neuroinvasive capacity of the SARS-CoV-2 through direct viral damage and indirect processes entering the CNS by different routes including the vasculature, the olfactory and trigeminal nerves, the cerebrospinal fluid, and the lymphatic system inducing a direct neurotoxicity. Furthermore, the pro-inflammatory cytokine storm and oxidative stress can induce microglial activation and damage to the blood-brain barrier, culminating in widespread neuroinflammatory process. This acute neurotoxicity is clinically expressed as anosmia and ageusia, headache, nausea and vomiting, but other neurologic manifestations such as acute cerebrovascular diseases, consciousness impairment due to encephalitis, and meningitis are also described. The PNS can also be affected by infectious damage and clinical manifestations including Guillain-Barre syndrome, polyneuritis cranialis, and Miller Fisher Syndrome. A special issue concerns the neurocognitive dysfunction and altered consciousness manifested as delirium, agitation and confusion. Non-specific symptoms such as dizziness, seizures can accompany clinical pictures. Regardless of the admission diagnosis, a high percentage of patients discharged from ICUs develop disabilities affecting physical, cognitive and psychological activities. The symptoms such as asthenia, memory disturbances, depression, sleep disturbances, anxiety, and Post-traumatic stress disorder (PTSD), configure the so-called Post-intensive Care Syndrome (PICS) Multimodal management during the ICU stay and implementation of follow-up programs at patient discharge can reduce the incidence of this syndrome, improving the quality of life of surviving patients. In this complex scenario, a careful clinical approach through reliable diagnostic tools, and epidemiological studies aimed at evaluating the dimensions of the problem also in economic terms, is urgently needed. This book represents a valuable aid for all those healthcare professionals (intensivists, neurologist and psychiatrists, as well) involved in the management of these critically ill patients.

ISBN: 9783030867058

Standard No.: 10.1007/978-3-030-86705-8doiSubjects--Topical Terms:

3591157
COVID-19 (Disease)
--Pathophysiology.

LC Class. No.: RA644.C67 / C37 2022

Dewey Class. No.: 616.2414

Features and management of acute and chronic neuro-covid
LDR:03965nmm a2200325 a 4500 001 2296464
003 DE-He213
005 20211127162931.0
006 m d
007 cr nn 008maaau
008 230324s2022 sz s 0 eng d
020 $a 9783030867058 $q (electronic bk.)
020 $a 9783030867041 $q (paper)
024 7 $a 10.1007/978-3-030-86705-8 $2 doi
035 $a 978-3-030-86705-8
040 $a GP $c GP
041 0 $a eng
050 4 $a RA644.C67 $b C37 2022
072 7 $a MMKL $2 bicssc
072 7 $a MED015000 $2 bisacsh
072 7 $a MKPL $2 thema
082 0 4 $a 616.2414 $2 23
090 $a RA644.C67 $b C336 2022
100 1 $a Cascella, Marco. $3 2203715
245 1 0 $a Features and management of acute and chronic neuro-covid $h [electronic resource] / $c by Marco Cascella, Elvio De Blasio.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2022.
300 $a xix, 158 p. : $b ill. (some col.), digital ; $c 24 cm.
505 0 $a Introduction -- Part I. Pathophysiology of COVID-19-associated neurotoxicity -- An update on preclinical findings -- Ongoing clinical investigations -- Perspectives -- Part II. Clinical manifestations of acute neurotoxicity -- Clinical features -- CNS complications -- PNS complications -- Diagnosis -- Management -- Perspectives -- Part III. Neurological and psychiatric sequelae in COVID-19 survivors -- Clinical features -- Neurological late complications -- psychological and psychiatric sequelae -- Diagnosis -- Tools -- The role of imaging -- Preventive strategies -- Social and economic impact -- Multidisciplinary management -- Perspectives.
520 $a This book underlines how COVID-19 is a multisystem inflammatory disease and how its pathophysiology can predispose to an increased risk of neurological issues. Several scientific pieces of evidence showes the mechanisms underlying the neuroinvasive capacity of the SARS-CoV-2 through direct viral damage and indirect processes entering the CNS by different routes including the vasculature, the olfactory and trigeminal nerves, the cerebrospinal fluid, and the lymphatic system inducing a direct neurotoxicity. Furthermore, the pro-inflammatory cytokine storm and oxidative stress can induce microglial activation and damage to the blood-brain barrier, culminating in widespread neuroinflammatory process. This acute neurotoxicity is clinically expressed as anosmia and ageusia, headache, nausea and vomiting, but other neurologic manifestations such as acute cerebrovascular diseases, consciousness impairment due to encephalitis, and meningitis are also described. The PNS can also be affected by infectious damage and clinical manifestations including Guillain-Barre syndrome, polyneuritis cranialis, and Miller Fisher Syndrome. A special issue concerns the neurocognitive dysfunction and altered consciousness manifested as delirium, agitation and confusion. Non-specific symptoms such as dizziness, seizures can accompany clinical pictures. Regardless of the admission diagnosis, a high percentage of patients discharged from ICUs develop disabilities affecting physical, cognitive and psychological activities. The symptoms such as asthenia, memory disturbances, depression, sleep disturbances, anxiety, and Post-traumatic stress disorder (PTSD), configure the so-called Post-intensive Care Syndrome (PICS) Multimodal management during the ICU stay and implementation of follow-up programs at patient discharge can reduce the incidence of this syndrome, improving the quality of life of surviving patients. In this complex scenario, a careful clinical approach through reliable diagnostic tools, and epidemiological studies aimed at evaluating the dimensions of the problem also in economic terms, is urgently needed. This book represents a valuable aid for all those healthcare professionals (intensivists, neurologist and psychiatrists, as well) involved in the management of these critically ill patients.
650 0 $a COVID-19 (Disease) $x Pathophysiology. $3 3591157
650 0 $a Neurotoxicology. $3 655637
650 0 $a Neurologic manifestations of general diseases. $3 679987
650 1 4 $a Intensive / Critical Care Medicine. $3 894417
650 2 4 $a Neurology. $3 588698
650 2 4 $a Psychiatry. $3 517037
650 2 4 $a Public Health. $3 624351
700 1 $a De Blasio, Elvio. $3 3591156
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer Nature eBook
856 4 0 $u https://doi.org/10.1007/978-3-030-86705-8
950 $a Medicine (SpringerNature-11650)