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[ subject:"Public health." ]
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Helicobacter pylori transmission and...
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Brown, Linda Morris.
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Helicobacter pylori transmission and risk factors for infection in rural China.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Helicobacter pylori transmission and risk factors for infection in rural China./
作者:
Brown, Linda Morris.
面頁冊數:
208 p.
附註:
Source: Dissertation Abstracts International, Volume: 61-06, Section: B, page: 3021.
Contained By:
Dissertation Abstracts International61-06B.
標題:
Public health. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=9973804
ISBN:
9780599790230
Helicobacter pylori transmission and risk factors for infection in rural China.
Brown, Linda Morris.
Helicobacter pylori transmission and risk factors for infection in rural China.
- 208 p.
Source: Dissertation Abstracts International, Volume: 61-06, Section: B, page: 3021.
Thesis (Dr.P.H.)--Uniformed Services University of the Health Sciences, 2000.
This item must not be sold to any third party vendors.
Helicobacter pylori (H. pylori) is one of the most common bacterial infections among humans, but little is known about its mode of transmission. A cross-sectional study of 3288 adults aged 35--69 from Shandong Province, China was conducted to assess some possible risk factors that may be associated with H. pylori infection in this high prevalence area of China. In-person home interviews (lasting approximately 15 minutes) were conducted in Chinese from October 1997--May 1998. The response rate was 96.4%. Maximum likelihood estimates and bootstrap confidence intervals (CI) of the association between the prevalence of H. pylori infection and demographic, lifestyle and some common environmental exposures were computed using polychotomous logistic regression.
ISBN: 9780599790230Subjects--Topical Terms:
534748
Public health.
Helicobacter pylori transmission and risk factors for infection in rural China.
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Helicobacter pylori (H. pylori) is one of the most common bacterial infections among humans, but little is known about its mode of transmission. A cross-sectional study of 3288 adults aged 35--69 from Shandong Province, China was conducted to assess some possible risk factors that may be associated with H. pylori infection in this high prevalence area of China. In-person home interviews (lasting approximately 15 minutes) were conducted in Chinese from October 1997--May 1998. The response rate was 96.4%. Maximum likelihood estimates and bootstrap confidence intervals (CI) of the association between the prevalence of H. pylori infection and demographic, lifestyle and some common environmental exposures were computed using polychotomous logistic regression.
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The H. pylori serostatus of the study participants was positive 60.6%, negative 31.0%, and indeterminate 8.4%. Source of drinking water, especially water from a shallow village well (OR = 1.8, 95%Cl = 1.4--2.3), was associated with increased prevalence of H. pylori infection. ORs were also elevated for infrequent hand washing before meals (OR = 1.6, 95%Cl = 1.0--2.5) and bathing in a pond or ditch (OR = 1.6, 95%Cl = 1.0--2.4). ORs were also associated with median village education level, ranging from 1.0 for villages classified as high, to 1.7 (95%Cl = 1.4--2.1) for villages classified as medium, to 2.4 (95%Cl = 2.0--3.0) for villages classified as low. ORs decreased slightly with increased consumption of all allium vegetables combined. The ORs were reduced for having a cat as a pet during childhood (OR = 0.7, 95%Cl = 0.5--1.0) and/or adulthood (OR = 0.6, 95%Cl). No significant associations were seen with any measure of cigarette smoking or alcoholic beverage consumption. Additionally, crowding or density factors as a child were not related to a higher prevalence of H. pylori infection as an adult.
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The results of the multi-variate modeling revealed prevalence rates that ranged from 75% to 46%, prevalence rate ratios that ranged from 1.0--1.5, and relative odds ratios that ranged from 1.0--8.6. Although a lack of heterogeneity in the population may have hampered the ability to detect actual associations, the finding that water may contribute to H. pylori infection deserves further evaluation. It is also noteworthy that cat ownership was not associated with an increased prevalence of H. pylori. The results of this study suggest that person-to-person and waterborne transmission, but not zoonotic transmission, are likely routes of H. pylori infection in this rural Chinese population.
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http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=9973804
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